Protein biochips are widely recognized as critical tools for achieving a more global, integrated understanding of biology and human disease.

 

The book takes an interdisciplinary approach by integrating elements of materials science, chemistry, protein engineering, and physics in a non-technical manner. It begins with an introduction to the field, chip design and development, and assays. The author then delves into problems addressed by protein biochips, including: disease biomarker applications, early tumor risk assessment, screening for drug discovery, and clinical trial design. The book concludes with a discussion of future directions.

 

Key features:

·         Provides a comprehensive yet approachable reference for the field

·         Offers a practical guide to how protein biochips are designed, built, and applied to various problems in biology and medicine

·         Accessible to tool developers and end users involved in drug development, clinical diagnosis, and medical research

·         Discusses multitarget screening, protein profiling, large-scale protein arrays, and multiplexing

·         Covers the range of applications in basic and clinical research

·         Well illustrated with numerous diagrams, tables, schemes, microarray images, and photomicrographs

·         Boxes highlight key processes and protocols

·         Includes contributions from luminaries who offer a unique and personal view on various key topics

·         Written by a pioneer in the field