This book constitutes the refereed proceedings of the First International Conference on Industrial Applications of Holonic and Multi-Agent Systems, HoloMAS 2003, held in Prague, Czech Republic in September 2003.The 29 revised full papers presented were carefully reviewed and selected from 43 submissions. The papers are organized in topical sections on holonic manufacturing systems-device control, foundations and platforms, sheduling and resource allocation, simulation and integration, multi-agent systems, and applications.