This two-volume set (CCIS 955 and CCIS 956) constitutes the refereed proceedings of the Second International Conference on Advanced Informatics for Computing Research, ICAICR 2018, held in Shimla, India, in July 2018. The 122 revised full papers presented were carefully reviewed and selected from 427 submissions. The papers are organized in topical sections on computing methodologies; hardware; information systems; networks; security and privacy; computing methodologies.