This textbook provides undergraduate students with comprehensive and accessible instruction on the fundamentals and cornerstone tools of chemometrics — a branch of analytical chemistry devoted to the optimization and implementation of analytical methods and the use of statistical and informatic tools to derive information. Readers will receive detailed and practical training in how to devise efficient and reliable analytical methodologies (using experimental design and signal calibration), as well as how to extract meaningful information from their data (using data mining techniques). The exercises contained within the volume will provide easy-to-follow standard protocols and guide students in the use of valuable and freely available open-source software.This book is a much-needed tool for undergraduate students in the modern educational environment. As European universities steadily converge around the EHEA (European Higher Education Area), the amount of time granted for theoretical and practical lessons in the classroom is being dramatically reduced. In the field of chemometrics, the available textbooks are often too technical or advanced for most inexperienced and untrained undergraduates. This textbook bridges this gap, providing students with the support and dedicated software they require.