Based on the authors' courses on cardiovascular fluid mechanics, this textbook is ideal for an introductory course on fluid mechanics in the human circulation. It covers fluid and solid mechanics as well as cardiovascular physiology; vascular implants and measurement techniques in the cardiovascular system; design and fluid mechanical evaluation of artificial heart valves; and fluid mechanical alterations related to vascular graft and stent implants. The book includes models illustrating fluid mechanics in the human circulation at the arterial level and detailed derivations of classic solutions and real-life applications.