Pharmacokinetics, the study of the movement of chemicals within the body, is a vital tool in assessing the risk of exposure to environmental chemicals. This book—a collection of papers authored by experts in academia, industry, and government—reviews the progress of the risk-assessment process and discusses the role of pharmacokinetic principles in evaluating risk. In addition, the authors discuss software packages used to analyze data and to build models simulating biological phenomena. A summary chapter provides a view of trends in pharmacokinetic modeling and notes some prospective fields of study.

Table of Contents


Front Matter
I. Introduction: The Problem and an Approach
II. Mathematical Modeling
III. Generalizations and Extrapolations
IV. Uncertainties: Integration with Risk Assessment and Resources
V. Poster Session
VI. Applications of Mathematical Modeling
VII. Summary: Prospectives and Future Directions
Perspectives
Index