This book presents the proceedings of the 19th International Conference of the Indian Society of Ergonomics (HWWE), held in Guwahati, India, on December 1-3, 2021. By highlighting the latest theories and models, as well as cutting-edge technologies and applications, and by combining findings from a range of disciplines including engineering, design, health care, management, computer science, and behavioral science, it provides researchers and practitioners alike with a comprehensive, timely guide on user-centered design for quality life, human factors and ergonomics, design applications, cognitive processing, and response. It also offers an excellent source of innovative ideas to stimulate future discussions and developments aimed at applying knowledge and techniques to optimize system performance, while at the same time promoting the health, safety, and well-being of individuals. The proceedings includes papers from researchers and practitioners, scientists and physicians, institutional leaders, managers, and policy makers that contribute to constructing the human factors and ergonomics approach across a variety of methodologies, domains, and productive sectors.