This is the most complete and authoritative review guide to prepare for certification, recertification/maintenance of certification, CME - or for use as a clinical refresher! This book contains over 1,000 revised and updated exam-type questions with fully explained answers - now, more case-based and clinically-oriented than ever before! The answers are referenced to, and reflect the new content from, the leading text in internal medicine, "Harrison's Principles of Internal Medicine, 16/e". It also includes references to recent journal articles. Hundreds of new Q&As reflect the new chapters and sections from the new "Harrison's, 16/e" textbook, including hormone replacement therapy, screening and prevention of disease, medical evaluation of the surgical patient, end-of-life care, critical care medicine, bioterrorism, and many others.It covers the entire spectrum of internal medicine, including cardinal manifestations of disease, hematology and oncology, infectious diseases, rheumatology and clinical immunology, and cardiovascular, kidney/urinary, respiratory, GI, genetic, endocrine, metabolic, and neurological disorders. The world of Harrison's is a step ahead of everyday practice.