This book gathers a collection of high-quality peer-reviewed research papers presented at the 6th International Conference on Data and Information Sciences (ICDIS 2024), held at Raja Balwant Singh Engineering Technical Campus, Agra, India, on May 24–25, 2024. The book covers all aspects of computational sciences and information security, including central topics like artificial intelligence, cloud computing, and big data. Highlighting the latest developments and technical solutions, it shows readers from the computer industry how to capitalize on key advances in next-generation computer and communication technology.