Providing a comprehensive and critical review of basic science and clinical aspects, this two-volume set covers the history, development, and current patterns of world-wide use of aspirin and ibuprofen. The coverage of pharmacokinetics and therapeutic effects highlights the factors affecting absorption, distribution, metabolism, and elimination. The books outline the chemical properties and synthesis of aspirin and its derivatives and considers the safety vesus efficacy issues and the pharmacoepidemiological data of ibuprofen. With the breadth and depth of scientific and clinical data available in one source, this set is the most definitive reference currently available on these drugs.