From childhood, Andre Carmichael suspected he had a twin, but his sister Sabrina consistently denied it. Then when Andre was 20, Sabrina told him she watched their abusive mother and older brother beat to death Andre's three-year-old twin, Latanisha, and hide her body in a bedroom closet, where it remained for two decades. Family Skeleton meticulously profiles the players in this horrific drama, while telling the story of the secret's revelation, the grim family dynamics that drove both the savage killing and the cover-up, and Andre and Sabrina's heroic attempts at healing.