This book constitutes the proceedings of the 12th International Conference on Parallel Computing Technologies, PaCT 2013, held in St. Petersburg, Russia, during September 30-October 4, 2013. The 41 full papers presented together with 2 invited papers were carefully reviewed and selected from 83 submissions. The papers are organized in topical sections on all technological aspects of the applications of parallel computer systems High level parallel programming languages and systems, methods and tools for parallel solution of large-scale problems, languages, environments and software tools supporting parallel processing, operating systems, scheduling, mapping, load balancing, general architectural concepts, cellular automata, performance measurement and analysis tools, teaching parallel processing, software for grid and cloud computing, scalable computing, fragmentation and aggregation of algorithms and programs as well as programs assembling and reuse.