Professor Klein has revised his acclaimed textbook of immunology as a result of feedback from his readership. The first edition received widespread praise for its clarity of explanation and won the Glaxo Prize for Textbook Writing. In his second edition, Professor Klein is joined by Dr Vaclav Horesji, who brings strength and expertise to the sections on cellular immunology.

As is expected, this book has been completely revised to reflect the enormous advances that have been made in our understanding of immunology in recent years. This edition contains the latest thinking on the role of natural killer cells, T-cell receptor signalling and accessory molecules, complement receptors, lymphokines and their receptors, toxic shock and LPs, and tumour immunology, to name but a few. As with the first edition, the authors have aimed to present only what is known and have kept the discussion of fashionable hypotheses to an absolute minimum. Finally, by including background material on methodology and basic biochemistry, the authors ensured that this book can be comprehended without referral to any other book.