This book constitutes the refereed proceedings of the First European Conference on Technology Enhanced Learning, EC-TEL 2006. The book presents 32 revised full papers, 13 revised short papers and 31 poster papers together with 2 keynote talks. Topics addressed include collaborative learning, personalized learning, multimedia content, semantic web, metadata and learning, workplace learning, learning repositories and infrastructures for learning, as well as experience reports, assessment, and case studies, and more.