Using a total systems management approach, System Engineering Management, Sixth Edition covers everything from initial establishment to system retirement, including design and development, testing, production, operations, maintenance, and support. This new edition focuses on the evolving discipline of engineering large complex systems. Updates and new topics include supply chain issues, environmental concerns, modeling trends, new concepts like Transdisciplinary Systems Engineering (TSE), resilient systems, data-driven decision-making, and recycling and reuse of complex systems. These updates consider technological advances, shifting resource availability and types, increasing data volumes, new design and implementation strategies, and more. This book emphasizes the need for system engineers and managers to be aware of these changes to improve their practice. Case studies illustrate real-world applications on both large- and small-scale systems in a variety of industries, and the companion website provides access to bonus case studies and helpful review checklists. The provided instructor's manual eases classroom integration, and new multiple-choice questions help reinforce the material. The challenges faced by system engineers are candidly addressed, with full guidance toward the tools they use daily to reduce costs and increase efficiency.