Plant cell signaling is an intensive research topic in which reductionism can be achieved when we investigate the systems of model plants. To continue our previous book entitled "Cell Signaling in Model Plants", the second volume explores more insights into the regulatory mechanisms of plant growth and development and eventually collects 20 publications that consist of one editorial, eleven original research articles and eight literature reviews. This book only presents a snapshot of this intensive field of plant biology, and we believe that with the rapid development of advanced technology such as integrative multi-omics and CRISPR genome editing, more and more critical networks of plant cell signaling will be unraveled in the future.