The Wei-Liang Chow and Kuo-Tsai Chen Memorial Conference was proposed and held by Prof S S Chern in Nankai Institute of Mathematics. It was devoted to memorializing those two outstanding and original Chinese mathematicians who had made significant contributions to algebraic geometry and algebraic topology, respectively. It also provided a forum for leading mathematicians to expound and discuss their views on new ideas in these fields, as well as trends in 21st Century mathematics. About 100 mathematicians participated in the conference, including Sir Michael Atiyah, Jacob Palis, Phillip Griffiths, David Eisenbud, Philippe Tondeur, Yujiro Kawamata, Tian Gang, etc.This invaluable volume contains the selected papers presented at the conference. The topics include canonical maps of Gorenstein 3-folds, fundamental groups of algebraic curves, Chen's interated integrals, algebraic fiber spaces, and others.