This text addresses the needs of students in the biological sciences by teaching calculus in a biological context without reducing the course level. It is a calculus text, written so that a math professor without a biology background can teach from it successfully. New concepts are introduced in a three step manner. First, a biological example motivates the topic; second, the topic is then developed via a simple mathematical example; and third the concept is tied to deeper biological examples. This allows students: to see why a concept is important; to understand how to use the concept computationally; to make sure that they can apply the concept.