This proceedings volume is a collection of 35 chapters presented at the Second International Conference on Artificial Intelligence, Machine Learning and Intelligent Systems (ICAMS-2025), held at the National Institute of Technology Hamirpur, Himachal Pradesh, India, from 7–8 February 2025. It gathers chapters on artificial intelligence, machine learning and intelligence systems. The book discusses how artificial intelligence, machine learning and intelligent systems are revolutionizing engineering and commercial practices through applications of mathematics. Covering diverse topics such as facial recognition security, cryptocurrency and blockchain technologies, automated trading, sustainable inventory management, personalized recommendation systems and IoT-driven smart solutions, the book highlights both theoretical advancements and practical implementations of mathematics across a wide range of disciplines.