Since its establishment by USDA regulation in the 1980s, the Institutional Animal Care and Use Committee(IACUC) has evolved as the premiere US instrument for animal welfare supervision. The IACUC Handbook provides a foundation for those attempting to understand and implement the various responsibilities of this committee. This new edition features comprehensive updates for all pertinent federal laws, regulations, and policies. It incorporates revised suggestions on best-practice compliance from experienced professionals. With concise, easy-to-find information, it remains the reference of choice for researchers and professionals.