This book features a collection of high-quality, peer-reviewed papers presented at the 8th International Conference on Intelligent Computing and Communication (ICICC 2025) organized by CMR Technical Campus (CMRTC), Hyderabad, Telangana, India, on September 26–27, 2025. It focuses on innovation paradigms in system knowledge, intelligence, and sustainability that can be applied to provide practical solutions to several problems in society, the environment, and industry. Further, the book also addresses the deployment of emerging computational and knowledge transfer approaches, optimizing solutions in various disciplines of science, technology, and health care.