This book has been written for students and researchers who wish to gain a working knowledge of time series analysis as applied in biomedical sciences. While intended as a text for graduate and undergraduate students in statistics and biostatistics, it covers a wide range of parametric, nonparametric and multi-scale methods for the analysis of stochastic processes coming from biology, medicine, epidemiology and neuroscience. The book assumes only a basic knowledge of calculus, matrix algebra and elementary statistics.