This book offers a comprehensive collection of 36 research contributions on the transformative role of soft computing techniques such as fuzzy logic, neural networks, genetic algorithms, and hybrid methodologies in solving complex problems in healthcare. By aligning its themes with Sustainable Development Goals (SDG 3: Good Health and Wel-Being), the book offers a comprehensive analysis of how these technologies are being integrated into medical diagnosis, predictive modeling, disease classification, personalized medicine and healthcare management. Through an exploration of current trends, research advancements and practical implementations, the book demonstrates the immense potential of soft computing to improve healthcare outcomes. It features a wide array of applications, including diagnostic systems for diseases such as cancer, Alzheimer's and cardiovascular conditions, as well as personalized treatment recommendations, patient monitoring systems and medical image analysis. It is aimed at researchers, practitioners and healthcare professionals, seeking to explore and apply advanced computational techniques to the medical field, providing both theoretical insights and practical applications.