This volume constitutes the refereed proceedings of the 12th Asian Conference on Intelligent Information and Database Systems, ACIIDS 2020, held in Phuket, Thailand, in March 2020. The total of 50 full papers accepted for publication in these proceedings were carefully reviewed and selected from 180 submissions. The papers are organized in the following topical sections: ​advanced big data, machine learning and data mining; industry applications of intelligent methods and systems; artificia intelligence, optimization, and databases in practical applications; intelligent applications of internet of things; recommendation and user centric applications of intelligent systems.