In this Special Issue on symmetry, we mainly discuss the application of symmetry in various structural health monitoring. For example, considering the health monitoring of a known structure, by obtaining the static or dynamic response of the structure, using different signal processing methods, including some advanced filtering methods, to remove the influence of environmental noise, and extract structural feature parameters to determine the safety of the structure. These damage diagnosis methods can also be effectively applied to various types of infrastructure and mechanical equipment. For this reason, the vibration control of various structures and the knowledge of random structure dynamics should be considered, which will promote the rapid development of the structural health monitoring. Among them, signal extraction and evaluation methods are also worthy of study. The improvement of signal acquisition instruments and acquisition methods improves the accuracy of data. A good evaluation method will help to correctly understand the performance with different types of infrastructure and mechanical equipment.