This is the 1st edition of the book Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings). The text is comprehensive, updated as per the present day requirements in the subject of infertility. In this edition of the book an effort is made to highlight the special problems and hurdles to provide infertility treatment in low resource setups. The book has 26 chapters. The first chapter deals with history of human assisted reproductive technology. Chapter two provides a comprehensive description of infertility in developing world. Next four chapters are dedicated to ART unit in low resource setting. Chapters from 9 to 12 deal with different conditions associated with infertility. Subsequent chapters describe setting up of ART unit, assisted reproductive technology and law and ethics related to ART. A comprehensive index is given at last.