This book is mainly focused on the climate change in Southeast Asia and its adjacent regions. It summarizes results from recent scientific research based on observational analysis, data diagnosis, theoretical analysis, and model simulations. The book covers the following research areas: (1) characteristics and mechanisms of spring–summer atmospheric circulation systems, (2) ocean-atmosphere-land interaction and climate variability, (3) climate effect of the Tibetan Plateau, (4) attribution of regional climate change and feedback/impact of regional climate on the global climate, and (5) seasonal-to-subseasonal climate prediction. It is anticipated that the book provides useful information for enhancing our understanding of the change in climate over Southeast Asia and the adjacent regions.